Bachelor and Master Thesis in Microbiome Manipulation

Bachelor and Master Thesis in Microbiome Manipulation 102383 Full time Neuherberg near Munich We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.This is what drives us. Why not join us and make a difference? The research of the Deng Lab at the Institute of Virology focuses on using integrative approaches combining single-cell technologies, culture-independent techniques, multi-omics, and machine learning to understand the underlying mechanisms of phage-host interactions and their impact on the human host. We apply the knowledge gained to develop novel phage-based therapeutics for i) targeting drug-resistant bacteria, and ii) preventing or iii) ameliorating severity in dysbiosis associated diseases and conditions, such as inflammatory bowel disease (IBD), colorectal cancer (CRC), graft versus host disease (GVHD), allergy, and much more by manipulating the human microbiota. Prof. Matthias Tschöp (Dr. Med., Dr. hc.), CEO of Helmholtz Munich: "We believe that excellent research requires a range of different perspectives. Diverse teams reach better solutions and are more innovative in their research topics.Establishing our Diversity Management Strategy demonstrates our commitment to ensuring an appreciative company culture based on mutual respect. We are also implementing diversity-sensitive processes throughout our whole organization." Your tasks Isolation, characterization, and preparation of phages for potential therapeutic useStudying how phages interact with their target bacteria in both in vitro and in vivoStudying the impact of phage infection on gut bacterial communities’ composition in RobogutEvaluating the efficacy of phage based tools for engineering the human microbiome in ex vivo Your profile Student of Life Scienes (incl. Biology, Microbiology, Biochemistry and Biotechnology)Good written and spoken English skillsImmatriculation in a German UniversityWillingness to learn Since 2005, we hold the TOTAL E-QUALITY award for exemplary action in the sense of an equal-opportunity organizational culture.Helmholtz Munich is actively committed to diversity and inclusion in practice and is sustainably committed to equality. The Diversity Charter has set itself the goal of promoting diversity in the world of work. By signing the charter, we commit ourselves to create an appreciative working environment for all employees. This position has a fixed term of 6 months.We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference.If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree.